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Illustrated by Erin Rommel & Sabrina Bezerra
Anyone who menstruates will likely be well acquainted with toxic shock syndrome (TSS), a rare but fatal infection highly associated with tampons.
Whether or not you use tampons, TSS is like an urban legend: very few have experienced it IRL, but everyone knows about – and is scared of it. Unfortunately TSS is very real, but how worried should you be?
Toxic shock syndrome causes
The biggest misconception about TSS is that it’s caused by tampons, but that’s simply not true. TSS is not caused by tampons, it’s simply linked to tampons – remember: correlation does not mean causation. TSS is actually caused by Staphylococcus aureus and Streptococcus pyogenes, two bacteria commonly referred to as Staph and Strep.
However, simply being exposed to these bacteria isn’t enough to develop TSS, because Staph and Strep usually already inhabit different parts of your body, including your throat, nostrils, vagina and rectum. They are harmless unless they multiply very quickly, at which point they produce a toxin (unimaginatively) called Toxic Shock Syndrome Toxin (TSST). If TSST enters your bloodstream, they can set off an immune cascade that compromises normal organ functions and damage tissue, with potentially fatal outcomes, but this process doesn’t require tampons or menstruation in order to occur.

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Toxic shock syndrom symptoms
TSS typically manifests with a rapid onset of:
- flu-like symptoms, including sudden fever, chills
- low blood pressure
- headache
- muscle aches
- vomiting and/or diarrhoea.
- A rash similar to sunburn, that is typically more severe over the palms of your hands and soles of your feet.
How do you get toxic shock from a tampon?
“The risk of developing TSS, whether it’s menstrual or non-menstrual, is about 1 in a million,” explains Dr. Harry Baxter, Daye’s Deputy Head of Research.
“Most non-menstrual cases are associated with burns or skin and soft tissue infections and appear to affect males and females equally.” TSS can affect anyone, whether they’re a menstruating human, a man, or child. So why do tampons get such a bad rap?
We still don’t know exactly how tampons are linked to the development of TSS, but the theory is that when left inside your vagina for too long, tampons create the perfect breeding ground for Staph bacteria to flourish and take over.
However, this is true for any device that is inserted in the vagina, and left there for a prolonged period of time. In fact, menstrual cups and barrier methods of contraception like caps and diaphragms are not risk-free, and have also been linked to TSS.
“Obviously, overgrowth of bad bacteria causes other issues beyond TSS, and would increase your risk of bacterial vaginosis and thrush,” warns Dr. Baxter, which is why you should change your tampon every 4-8 hours.

Not only is TSS not caused by tampons, but it’s incredibly rare, because your immune system does a great job at protecting you from it. “Most people produce an antibody that protects against Toxic Shock Syndrome Toxin,” Dr. Baxter explains. “To develop TSS, you both need the toxin and have to be unlucky enough to not have the antibody,” and that’s quite a rare combination. On top of that, the good bacteria in your vaginal microbiome fight off bad bacteria like Staph.